(1R,2R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-hydroxymethyl-cyclopentanecarboxylic acid ethyl ester → HCID 178472524, Verbindung

HRID 1367507

Reaktionsgleichung

Reaktionsgleichung von HRID 1367507
[CH2:1]([O:3][C:4]([C@@H:6]1[CH2:10][CH:9]([O:11][Si:12]([C:15]([CH3:18])([CH3:17])[CH3:16])([CH3:14])[CH3:13])[CH2:8][C@H:7]1[CH2:19][OH:20])=[O:5])[CH3:2].[N:21]1[C:26]([OH:27])=[CH:25][CH:24]=[C:23](O)[N:22]=1>>[CH2:1]([O:3][C:4]([C@@H:6]1[CH2:10][CH:9]([O:11][Si:12]([C:15]([CH3:16])([CH3:18])[CH3:17])([CH3:13])[CH3:14])[CH2:8][C@H:7]1[CH2:19][O:20][C:23]1[N:22]=[N:21][C:26]([OH:27])=[CH:25][CH:24]=1)=[O:5])[CH3:2]

Komponenten

3

Edukt 2

HCID 59619451(1R,2R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-hydroxymethyl-cyclopentanecarboxylic acid ethyl esterHCID 178516298pyridazine-3,6-diol

Produkt 1

HCID 178472524HCID 178472524, Verbindung

Versuchsvorschrift

The title compound was synthesized in analogy to Example 68/69, Step 5, from (1R,2R)-4-(tert-butyl-dimethyl-silanyloxy)-2-hydroxymethyl-cyclopentanecarboxylic acid ethyl ester (epimeric mixture, Example 69, Step 4) and pyridazine-3,6-diol to afford the desired product as a white gum. MS (EI): 385.3 (M−H)−.

Quellen und Nachweise

ORD-Eintrag
ord-76fc2189f49a4c4eb75f538a3518fded
Quelldatensatz
uspto-grants-2011_02
Patentnummer
US07893099B2

Verknüpfte Notizen

Wird geladen…