Dichloromethane → Methyl 4-((3-(2-amino-4-methyl-6-(pentylamino)pyrimidin-5-yl)propyl)(3-(2-methoxy-2-oxoethyl)benzyl)amino)-4-oxobutanoate

Reaktionsgleichung

[C:31]([CH2:32][CH2:33][C:34](=[O:35])[O-:36])(=[O:37])[O:38][CH3:39].[Cl:64][CH2:65][Cl:66].[NH2:1][c:2]1[n:3][c:4]([NH:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[c:5]([CH2:9][CH2:10][CH2:11][NH:12][CH2:13][c:14]2[cH:15][c:16]([CH2:20][C:21](=[O:22])[O:23][CH3:24])[cH:17][cH:18][cH:19]2)[c:6]([CH3:8])[n:7]1.[P-:40]([F:41])([F:42])([F:43])([F:44])([F:45])[F:46].[n:47]1([O:48][C:49]([N:50]([CH3:51])[CH3:52])=[N+:53]([CH3:54])[CH3:55])[c:56]2[n:57][cH:58][cH:59][cH:60][c:61]2[n:62][n:63]1>>[NH2:1][c:2]1[n:3][c:4]([NH:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[c:5]([CH2:9][CH2:10][CH2:11][N:12]([CH2:13][c:14]2[cH:15][c:16]([CH2:20][C:21](=[O:22])[O:23][CH3:24])[cH:17][cH:18][cH:19]2)[C:34]([CH2:33][CH2:32][C:31](=[O:37])[O:38][CH3:39])=[O:35])[c:6]([CH3:8])[n:7]1