Triethyl orthoacetate → 4(3H)-Quinazolinone, 2-methyl-3-(2-pyridyl)-

Beteiligte Stoffe

Reaktionsschritte

A mixture of 72 (3 g, 0.015 mol) and 1,1,1-triethoxy-ethane (5 g, 0.045 mol) were heated for 7 hours. The reaction mixture was poured into water, filtered, and the precipitate was washed with water and recrystallized from EtOH to yield 73 (2.5 g, 75%). M. Wt. 237. LCMS [M+H]+=238.

Herkunft & Nachweise