2-[2-(4-Methylpiperazino)-2-oxoethyl]phenyl N-octadecylcarbamate → HCID 18520252, Verbindung

HRID 1368385Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1368385
[ClH:1].C(OCC)(=O)C.[CH2:8]([NH:26][C:27](=[O:45])[O:28][C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=1[CH2:35][C:36]([N:38]1[CH2:43][CH2:42][N:41]([CH3:44])[CH2:40][CH2:39]1)=[O:37])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]>C(OCC)(=O)C>[ClH:1].[CH2:8]([NH:26][C:27](=[O:45])[O:28][C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=1[CH2:35][C:36]([N:38]1[CH2:39][CH2:40][N:41]([CH3:44])[CH2:42][CH2:43]1)=[O:37])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]

Komponenten

4

Edukt 2

HCID 185202532-[2-(4-Methylpiperazino)-2-oxoethyl]phenyl N-octadecylcarbamateHCID 21866389Hydrogen chloride-ethyl acetate

Produkt 1

HCID 18520252HCID 18520252, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

4N Hydrochloric acid/ethyl acetate solution (1.40 ml) was added to a solution containing 2-[2-(4-methylpiperazino)-2-oxoethyl]phenyl N-octadecylcarbamate (2.50 g) in ethyl acetate (25 ml) at room temperature. After being stirred for 30 minutes, the reaction mixture was concentrated. The residue was recrystallized with the mixed solution of ethyl acetate-ethanol, thereby yielding the entitled compound (2.52 g) as white solid.

Aufarbeitung

  1. concentrationthe reaction mixture was concentrated
  2. customThe residue was recrystallized with the mixed solution of ethyl acetate-ethanol

Quellen und Nachweise

ORD-Eintrag
ord-361ecb7a0c8b4b3d982365cd87b73bac
Quelldatensatz
uspto-grants-2003_06
Patentnummer
US06573297B2

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