6-Iodo-4-trifluoromethyl-isatin → HCID 18518539, Verbindung
Reaktionsgleichung
[F:1][C:2]([F:16])([F:15])[C:3]1[CH:11]=[C:10]([I:12])[CH:9]=[C:8]2[C:4]=1[C:5](=[O:14])[C:6](=[O:13])[NH:7]2.[CH:17]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH:20]=[CH:19][C:18]=1[Mg]Br>>[F:16][C:2]([F:15])([F:1])[C:3]1[CH:11]=[C:10]([I:12])[CH:9]=[C:8]2[C:4]=1[C:5]([OH:14])([C:19]1[CH:18]=[CH:17][C:26]3[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=3)[CH:20]=1)[C:6](=[O:13])[NH:7]2Komponenten
3
Versuchsvorschrift
The title compound (35.8 mg, 6.5%) was prepared from 4-trifluoromethyl-6-iodoisatin (400 mg, 1.17 mmol) and 2-naphthyl magnesium bromide by the procedure similar to that described in Example 1.
Quellen und Nachweise
- ORD-Eintrag
- ord-ee846b2354b34011911900d410fec525
- Quelldatensatz
- uspto-grants-2003_06
- Patentnummer