HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
7-Nitroindole → 7-Aminoindole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 7-Nitroindole | HCID 23396 | — |
| Edukt | Ammonium formate | HCID 2723923 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 7-Aminoindole | HCID 111634 | 99% |
Reaktionsschritte
Dissolve 7-nitroindole in ethanol and add ammonium formate (10 equivalents) and a catalytic amount of 10% palladium on carbon. Heat the mixture to reflux for 1 hr before cooling, filter through celite, and evaporate to provide the product as a purple solid (99%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07728150B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-d66e2b89479b4a10883eee173cc6ba93 |
| Quellennotiz | uspto-grants-2010_06 |