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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1370691Erstellt: 27. Oktober 2026

Decanoic Acid → N-alpha-decyl-L-phenylalanine 2-aminopyridine

https://huagongshe.com/reaction/1370691

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktDecanoic AcidHCID 2969—
EduktDicyclohexylcarbodiimideHCID 10868—
EduktN-alpha-t-BOC-L-phenylalanine 2-aminopyridineHCID 131722899—
ProduktN-alpha-decyl-L-phenylalanine 2-aminopyridineHCID 69929295—

Reaktionsschritte

The acylated phenylalanine anilide imprint molecule was synthesized in three steps. (1) N-α-t-BOC-L-phenylalanine was coupled with 2-aminopyridine using DCC to give N-α-t-BOC-L-phenylalanine-2-aminopyridine. (2) The a-amine was then deprotected with TFA to give N-α-L-phenylalanine-2-aminopyridine.(3) To create a compound having the properties of a surfactant, the free amine was then acylated with decanoic acid using DCC to give N-α-decyl-L-phenylalanine-2-aminopyridine.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06583191B2
Quelldatensatzuspto-grants-2003_06
ORD IDord-8356d47dea244ee092f64ce137f0af14
Quellennotizuspto-grants-2003_06