2,3,4-Trifluoroanisole → HCID 11974950, Verbindung

Reaktionsgleichung

CON(C)[C:4]([C:6]1[C:7]([NH2:15])=[N:8][C:9]([S:12][CH2:13][CH3:14])=[N:10][CH:11]=1)=[O:5].[F:17][C:18]1[C:23]([F:24])=[C:22]([F:25])[CH:21]=[CH:20][C:19]=1[O:26][CH3:27]>>[NH2:15][C:7]1[C:6]([C:4]([C:20]2[CH:21]=[C:22]([F:25])[C:23]([F:24])=[C:18]([F:17])[C:19]=2[O:26][CH3:27])=[O:5])=[CH:11][N:10]=[C:9]([S:12][CH2:13][CH3:14])[N:8]=1

Komponenten

Edukt 2

HCID 27769422,3,4-Trifluoroanisole

HCID 119748325-Pyrimidinecarboxamide, 4-amino-2-(ethylthio)-N-methoxy-N-methyl-

Produkt 1

HCID 11974950HCID 11974950, Verbindung

Versuchsvorschrift

The compound was prepared from 4-amino-2-ethylsulfanyl-pyrimidine-5-carboxylic acid methoxy-methyl-amide, Example 1, and 2,3,4-trifluoroanisole (Matrix) in an analogous manner as described in Example 169.

Quellen und Nachweise

ORD-Eintrag: ord-7649a581cc344112b1bee4c008681c5d
Quelldatensatz: uspto-grants-2007_01
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07157455B2

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