Ethylene Glycol → 2-Methyl-2-phenyl-1,3-dioxolane

HRID 13727

Reaktionsgleichung

Reaktionsgleichung von HRID 13727
[H][H].[C:3]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)(=[O:5])[CH3:4].[CH2:12](O)[CH2:13][OH:14]>C1C=CC=CC=1.C1(C)C=CC=CC=1>[CH3:4][C:3]1([C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=2)[O:14][CH2:13][CH2:12][O:5]1

Komponenten

6

Edukt 3

HCID 174Ethylene GlycolHCID 7410AcetophenoneHCID 178418361HCID 178418361, Verbindung3×

Produkt 1

HCID 1380062-Methyl-2-phenyl-1,3-dioxolane

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 241BenzeneLösungsmittelHCID 1140TolueneLösungsmittel

Versuchsvorschrift

Utilising known reaction conditions compounds of Formula 1, where R and R1 are hydrogen or R is hydrogen and R1 is a C1-40 alkyl, C2-40 alkenyl, C2-40 alkynyl, aryl or C1-8 alkylaryl fragment, readily catalyse the ketalisation of ketones. Standard conditions were used to conduct these reactions. For example heating under a Dean and Stark apparatus acetophenone and an excess of ethylene glycol in benzene or toluene in the presence of compounds of Formula 1 where R and R1 are hydrogen gave the desired product 2-methyl-2-phenyl-1,3-dioxolane in quantitative yield.

Quellen und Nachweise

ORD-Eintrag
ord-0ad007efb64947fdbba987e1e24ebec3
Quelldatensatz
uspto-grants-2010_06
Patentnummer
US07728159B2

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