HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Acetyl-5-nitroindolin-2-one → 1-Acetyl-5-aminoindolin-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Acetyl-5-nitroindolin-2-one | HCID 2839329 | — |
| Edukt | HCID 178418361 | HCID 178418361 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | 1-Acetyl-5-aminoindolin-2-one | HCID 12046998 | — |
Reaktionsschritte
30.0 g (136 mmol) of 1-acetyl-5-nitro-2-indolinone are dissolved in a mixture of 650 ml of dichloromethane and 650 ml of methanol and after the addition of 5 g of 10% palladium on activated charcoal the mixture is hydrogenated for 45 minutes with hydrogen. Then the catalyst is filtered off and evaporated down.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07160901B2 |
| Quelldatensatz | uspto-grants-2007_01 |
| ORD ID | ord-20d1f7e55882484bb6b38a2f3b1021d2 |
| Quellennotiz | uspto-grants-2007_01 |