1-(5,6,7,8-Tetrahydronaphthalen-1-yl)piperazine → 5-Methyl-7-{4-[4-(5,6,7,8-tetrahydro-naphthalen-1-yl)-piperazin-1-yl]-butoxy}-3,4-dihydro-1H-[1,8]naphthyridin-2-one

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1-(5,6,7,8-Tetrahydronaphthalen-1-yl)piperazine	HCID 98698	—
Edukt	4-(4-Methyl-7-oxo-5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yloxy)-butyraldehyde	HCID 21073350	—
Produkt	5-Methyl-7-{4-[4-(5,6,7,8-tetrahydro-naphthalen-1-yl)-piperazin-1-yl]-butoxy}-3,4-dihydro-1H-[1,8]naphthyridin-2-one	HCID 21073421	—

Reaktionsschritte

The title compound was prepared by reductive amination of 4-(4-methyl-7-oxo-5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yloxy)-butyraldehyde with 1-(5,6,7,8-tetrahydro-naphthalen-1-yl)-piperazine according to the above procedure. MS: APCI: M+1: 450.0 (Exact Mass: 448.28).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07160888B2
Quelldatensatz	uspto-grants-2007_01
ORD ID	ord-a05f6472d8fa4baeab359f3e06a2916c
Quellennotiz	uspto-grants-2007_01