1-Indan-4-yl-piperazine hydrochloride → 7-[4-(4-Indan-4-yl-piperazin-1-yl)-butoxy]-5-trifluoromethyl-3,4-dihydro-1H-[1,8]naphthyridin-2-one

Beteiligte Stoffe

Reaktionsschritte

In a manner similar to that of other examples above, 1-indan-4-yl-piperazine hydrochloride was coupled by reductive amination to 4-(7-oxo-4-trifluoromethyl-5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yloxy)-butyraldehyde followed by typical workup and purification to give the title compound. MS: APCI: M+1: 489.4 (Exact Mass: 488.24).

Herkunft & Nachweise