Triphenylphosphine → (3-Methoxybenzyl)triphenylphosphonium Chloride

HRID 1374845Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1374845
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH2:6][Cl:7].[C:11]1([P:17]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>CN(C)C=O>[Cl-:7].[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH2:6][P+:17]([C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1)([C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1

Komponenten

4

Edukt 2

HCID 11776TriphenylphosphineHCID 699943-Methoxybenzyl chloride

Produkt 1

HCID 11407464(3-Methoxybenzyl)triphenylphosphonium ChlorideAusbeute 61 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Reaktionsbedingungen

Temperatur
150 °C

Versuchsvorschrift

3-Methoxybenzyl chloride (1.05 g, 6.69 mmol), triphenylphosphine (1.75 g, 6.67 mmol) was dissolved in dimethylformamide (10 ml) and heated at 150° C. for 40 minutes. The reaction mixture was cooled to room temperature, and the solid precipitated was collected by filtration and washed and ethyl ether, and then dried under reduced pressure to obtain the title compound as colorless solid 1.70 g (yield: 61%).

Aufarbeitung

  1. temperatureThe reaction mixture was cooled to room temperature
  2. customthe solid precipitated
  3. filtrationwas collected by filtration
  4. washwashed
  5. dry with materialethyl ether, and then dried under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-dd329a8845a841a2858c3b6ba450995c
Quelldatensatz
uspto-grants-2007_01
Patentnummer
US07166617B2

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