Ethyl 4-[2,2-dimethyl-4-(tol-4-yl)-benzo(1,2-g)-chrom-3-en-7-yl]benzoate → 4-(2,2-Dimethyl-4-p-tolyl-2H-benzo[g]chromen-7-yl)-benzoic acid

HRID 1375273

Reaktionsgleichung

Reaktionsgleichung von HRID 1375273
CC1SC(C2C3C(=CC4C(C=3)=C(C3C=CC(C(O)=O)=CC=3)C=CC=4)C(C)(C)CC=2)=CC=1.[CH3:32][C:33]1([CH3:65])[CH:42]=[C:41]([C:43]2[CH:48]=[CH:47][C:46]([CH3:49])=[CH:45][CH:44]=2)[C:40]2[C:35](=[CH:36][C:37]3[CH:53]=[CH:52][C:51]([C:54]4[CH:64]=[CH:63][C:57]([C:58]([O:60]CC)=[O:59])=[CH:56][CH:55]=4)=[CH:50][C:38]=3[CH:39]=2)[O:34]1>>[CH3:32][C:33]1([CH3:65])[CH:42]=[C:41]([C:43]2[CH:44]=[CH:45][C:46]([CH3:49])=[CH:47][CH:48]=2)[C:40]2[C:35](=[CH:36][C:37]3[CH:53]=[CH:52][C:51]([C:54]4[CH:64]=[CH:63][C:57]([C:58]([OH:60])=[O:59])=[CH:56][CH:55]=4)=[CH:50][C:38]=3[CH:39]=2)[O:34]1

Komponenten

3

Edukt 2

HCID 9933376Ethyl 4-[2,2-dimethyl-4-(tol-4-yl)-benzo(1,2-g)-chrom-3-en-7-yl]benzoate2×HCID 186200524-[1 (5-Methyl-thien-2-yl)3,4-dihydro-4,4-dimethyl-anthracen-8-yl]-benzoic acid2×

Produkt 1

HCID 98883854-(2,2-Dimethyl-4-p-tolyl-2H-benzo[g]chromen-7-yl)-benzoic acid

Versuchsvorschrift

By following the procedure employed for the preparation of 4-[1(5-methyl-thien-2-yl)3,4-dihydro-4,4-dimethyl-anthracen-8-yl]-benzoic acid (Compound 4), ethyl 4-[2,2-dimethyl-4-(tol-4-yl)-benzo(1,2-g)-chrom-3-en-7-yl]benzoate (Compound 9, 10 mg, 0.02 mmol), was converted into the title compound using LiOH in water (0.2 mL, 0.2 mmol). The title compound was obtained as an off white solid.

Quellen und Nachweise

ORD-Eintrag
ord-d619f19114ef480499ec5356f029f448
Quelldatensatz
uspto-grants-2007_01
Patentnummer
US07166726B2

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