Formaldehyde → N-methylene-1-methyl-1-(3,5-dichlorophenyl)ethylamine

HRID 1379573Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1379573
[CH3:1][C:2]([NH2:12])([C:4]1[CH:9]=[C:8]([Cl:10])[CH:7]=[C:6]([Cl:11])[CH:5]=1)[CH3:3].C=O.[C:15](=O)(O)[O-].[Na+]>>[CH2:15]=[N:12][C:2]([CH3:1])([C:4]1[CH:9]=[C:8]([Cl:10])[CH:7]=[C:6]([Cl:11])[CH:5]=1)[CH3:3]

Komponenten

4

Edukt 3

HCID 712FormaldehydeHCID 516892Sodium BicarbonateHCID 111950522-(3,5-Dichlorophenyl)propan-2-amine

Produkt 1

HCID 21223286N-methylene-1-methyl-1-(3,5-dichlorophenyl)ethylamine

Versuchsvorschrift

1-Methyl-1-(3,5-dichlorophenyl)ethylamine (7.5 g) was gradually added to formalin (37% aqueous HCHO solution) (4.6 g) at room temperature. This mixture was subjected as it is to reaction for 7 hours. A saturated sodium bicarbonate solution was added to the reaction mixture, the resultant was extracted with ether and this organic layer was washed with saturated saline solution, and then dried over anhydrous sodium sulfate. The solvent was removed by evaporation under reduced pressure to obtain 8.6 g of N-methylene-1-methyl-1-(3,5-dichloro-phenyl)ethylamine as white crystals.

Aufarbeitung

  1. customis to reaction for 7 hours
  2. extractionthe resultant was extracted with ether
  3. washthis organic layer was washed with saturated saline solution
  4. dry with materialdried over anhydrous sodium sulfate
  5. customThe solvent was removed by evaporation under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-52a6716a7b1e4e29b01bd2b73c8beb15
Quelldatensatz
uspto-grants-1997_09
Patentnummer
US05672566

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