Hydrazine → 4,5-Diamino-o-anisic acid

HRID 1381978Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1381978
[OH-].[Na+].[CH3:3][O:4][C:5]1[CH:13]=[C:12]([NH2:14])[C:11]([N+:15]([O-])=O)=[CH:10][C:6]=1[C:7]([O-:9])=[O:8].[Na+].NN>[Ni]>[CH3:3][O:4][C:5]1[CH:13]=[C:12]([NH2:14])[C:11]([NH2:15])=[CH:10][C:6]=1[C:7]([OH:9])=[O:8]

Komponenten

5

Edukt 3

HCID 9321HydrazineHCID 14798Sodium HydroxideHCID 21275767Sodium 2-methoxy-4-amino-5-nitrobenzoate

Produkt 1

HCID 1010174,5-Diamino-o-anisic acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 935NickelKatalysator

Versuchsvorschrift

reacting methyl-2-methoxy-4-acetylamino 5-nitrobenzoate with sodium hydroxide and then reducing the resulting sodium 2-methoxy-4-amino-5-nitrobenzoate intermediate with hydrazine in the presence of Raney nickel at ambient pressure to form a 2-methoxy-4,5-diaminobenzoic acid intermediate;

Quellen und Nachweise

ORD-Eintrag
ord-f1dd7f8f20be49548acecb85b6832d48
Quelldatensatz
uspto-grants-1989_02
Patentnummer
US04804765

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