HCID 178440264, Verbindung → 1h-Imidazole-5-carboxaldehyde, 4-propyl-

HRID 1382784Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1382784
[CH2:1]([C:4]1[NH:8][CH:7]=[N:6][C:5]=1[CH2:9][OH:10])[CH2:2][CH3:3]>O1CCOCC1.[O-2].[Mn+4].[O-2]>[CH2:1]([C:4]1[NH:8][CH:7]=[N:6][C:5]=1[CH:9]=[O:10])[CH2:2][CH3:3]

Komponenten

4

Edukt 1

HCID 178440264HCID 178440264, Verbindung

Produkt 1

HCID 135486171h-Imidazole-5-carboxaldehyde, 4-propyl-Ausbeute 73,6 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418406HCID 178418406, VerbindungKatalysatorHCID 312751,4-DioxaneLösungsmittel

Versuchsvorschrift

A mixture of 5-propyl-1H-imidazole-4-methanol (4.0 g) and manganese (IV) oxide (10.0 g) in 1,4-dioxan (150 ml) was heated at reflux under nitrogen for 1 h. The hot suspension was filtered (Hyflo), washed with hot 1,4-dioxan (100 ml) and evaporated to give the title compound (2.9 g) as a solid, m.p. 120°-124°.

Aufarbeitung

  1. temperaturewas heated
  2. temperatureat reflux under nitrogen for 1 h
  3. filtrationThe hot suspension was filtered (Hyflo)
  4. washwashed with hot 1,4-dioxan (100 ml)
  5. customevaporated

Quellen und Nachweise

ORD-Eintrag
ord-99de9a7c13e141b7a9764bad08659136
Quelldatensatz
uspto-grants-1989_02
Patentnummer
US04808581

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