Ammonia → Pyrido(4,3-d)pyrimidine-2,4(1H,3H)-dione, 1,3-dimethyl-

HRID 1382866Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1382866
C([C:3]1[C:4](=[O:17])[N:5]([CH3:16])[C:6](=[O:15])[N:7]([CH3:14])[C:8]=1[CH:9]=[CH:10][N:11](C)[CH3:12])=O.N>C(O)C>[CH3:14][N:7]1[C:8]2[CH:9]=[CH:10][N:11]=[CH:12][C:3]=2[C:4](=[O:17])[N:5]([CH3:16])[C:6]1=[O:15]

Komponenten

4

Edukt 2

HCID 222AmmoniaHCID 54245828HCID 54245828, Verbindung

Produkt 1

HCID 3086912Pyrido(4,3-d)pyrimidine-2,4(1H,3H)-dione, 1,3-dimethyl-Ausbeute 84,5 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

0.47 g of 5-formyl-1,3-dimethyl-6-(2-dimethylaminovinyl)uracil was dissolved in ethanol, and ammonia was added thereto. The solution was stirred for 30 min at room temperature. The precipitated crystals were separated from the solution by filtration and recrystallized from ethanol to give 0.32 g of 1,3-dimethylpyrido[4,3-d]pyrimidine-2,4-dione (Compound 1).

Aufarbeitung

  1. customThe precipitated crystals were separated from the solution by filtration
  2. customrecrystallized from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-aae985345d584ab5a9e0c8b770495557
Quelldatensatz
uspto-grants-1989_02
Patentnummer
US04808618

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