2-Bromopropane → 3-(3,5-Di-tertiary butyl-4-hydroxyphenyl)-1-isopropyl-1H-pyrazolo[3,4-b]pyridine
Reaktionsgleichung
[C:1]([C:5]1[CH:6]=[C:7]([C:16]2[C:24]3[C:19](=[N:20][CH:21]=[CH:22][CH:23]=3)[NH:18][N:17]=2)[CH:8]=[C:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:10]=1[OH:11])([CH3:4])([CH3:3])[CH3:2].[CH:25](Br)([CH3:27])[CH3:26]>>[C:1]([C:5]1[CH:6]=[C:7]([C:16]2[C:24]3[C:19](=[N:20][CH:21]=[CH:22][CH:23]=3)[N:18]([CH:25]([CH3:27])[CH3:26])[N:17]=2)[CH:8]=[C:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:10]=1[OH:11])([CH3:2])([CH3:3])[CH3:4]Komponenten
3
Versuchsvorschrift
3-(3,5-Di-tertiary butyl-4-hydroxyphenyl)-1-isopropyl-1H-pyrazolo[3,4-b]pyridine, melting at 147° C. is prepared by reacting the compound of Example 1 with isopropyl bromide similarly in Example 9, and recrystallizing from isopropyl ether.
Aufarbeitung
- customrecrystallizing from isopropyl ether
Quellen und Nachweise
- ORD-Eintrag
- ord-dae412835e5b4f45a814c10109b4c329