2-Trifluoroacetylphenol → [2-[2-(N-Dodecyl-N-methylamino)ethoxy]phenyl]-2,2,2-trifluoroethanone

HRID 1383898Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1383898
[F:1][C:2]([F:13])([F:12])[C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[OH:11])=[O:4].[CH2:14]([N:26]([CH2:28][CH2:29]O)[CH3:27])[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]>>[CH2:14]([N:26]([CH2:28][CH2:29][O:11][C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=1[C:3](=[O:4])[C:2]([F:12])([F:13])[F:1])[CH3:27])[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]

Komponenten

3

Edukt 2

HCID 27611642-TrifluoroacetylphenolHCID 10657884Dodecyl(2-hydroxyethyl)methylamine

Produkt 1

HCID 18319145[2-[2-(N-Dodecyl-N-methylamino)ethoxy]phenyl]-2,2,2-trifluoroethanoneAusbeute 61,2 %

Versuchsvorschrift

2-Trifluoroacetylphenol (Matsumoto, S.; Kobayashi, H. and Ueno, K. Bull. Chem. Soc. Jpn. 1969, 42, 960) (490 mg, 2.57 mmol) and 2-[N-dodecyl-N-methylamino] ethanol (627 mg, 2.58 mmol) were reacted by the general procedure as described in example 1 and afforded the title compound (654 mg, 61%) as a pale yellow oil.

Quellen und Nachweise

ORD-Eintrag
ord-e01239760fc14bd2aada696da08cc869
Quelldatensatz
uspto-grants-2001_07
Patentnummer
US06255496B1

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