Hydrochloric Acid → 2,3-Diaminophenol--hydrogen chloride (1/2)

Temperatur

50 °C

In a 250 ml single neck round bottom flask was added 2,3-diaminophenol (10 g, 80.55 mmol) to ethanol (100 ml). This mixture was heated to 50° C. to achieve dissolution. The resulting solution is cooled to −5 to 0° C. and an excess of anhydrous hydrogen chloride gas was added to form a viscous slurry. The resulting mixture was stirred for two hours at ˜0° C., then filtered, and rinsed with chilled methanol (30 ml). The solvents were removed in vacuo and the residue was dried overnight.

1. dissolutiondissolution
2. temperatureThe resulting solution is cooled to −5 to 0° C.
3. customto form a viscous slurry
4. filtrationfiltered
5. washrinsed with chilled methanol (30 ml)
6. customThe solvents were removed in vacuo
7. customthe residue was dried overnight

ORD-Eintrag

ord-8db2d0d1e5914a8a9fe096d494e21526

Quelldatensatz

uspto-grants-2001_07

DOI

10.6084/m9.figshare.5104873.v1

Patentnummer

US06255494B1