4-(Methanesulfonyl)-3-nitrobenzoic acid → 3-Amino-4-methylsulfonylbenzoic acid

HRID 1385035Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1385035
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][C:12]=1[S:13]([CH3:16])(=[O:15])=[O:14])[C:7]([OH:9])=[O:8])([O-])=O.[H][H]>[Ni].CO>[NH2:1][C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][C:12]=1[S:13]([CH3:16])(=[O:15])=[O:14])[C:7]([OH:9])=[O:8]

Komponenten

5

Edukt 2

HCID 27238714-(Methanesulfonyl)-3-nitrobenzoic acidHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 227288903-Amino-4-methylsulfonylbenzoic acid

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 935NickelKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

0.447 mol of 3-nitro-4-methylsulfonylbenzoic acid was reduced with hydrogen by employing 100 g of Raney nickel in 2.5 l of methanol. The mixture was then heated to reflux and filtered off hot with suction. The filtrate was concentrated.

Aufarbeitung

  1. temperatureThe mixture was then heated
  2. temperatureto reflux
  3. filtrationfiltered off hot with suction
  4. concentrationThe filtrate was concentrated

Quellen und Nachweise

ORD-Eintrag
ord-d021487c37664994ae4f0fac6f40a452
Quelldatensatz
uspto-grants-2001_07
Patentnummer
US06262074B1

Notizen zur Reaktion

Wird geladen…