2-Bromopropane → HCID 53710128, Verbindung

Reaktionsgleichung

[CH3:1][O:2][C:3]([C:5]1[CH:13]=[C:12]2[C:8]([C:9]([CH2:14][CH3:15])=[N:10][NH:11]2)=[CH:7][CH:6]=1)=[O:4].Br[CH:17]([CH3:19])[CH3:18]>>[CH3:1][O:2][C:3]([C:5]1[CH:13]=[C:12]2[C:8]([C:9]([CH2:14][CH3:15])=[N:10][N:11]2[CH:17]([CH3:19])[CH3:18])=[CH:7][CH:6]=1)=[O:4]

Komponenten

Edukt 2

HCID 63582-Bromopropane

HCID 178438014HCID 178438014, Verbindung

Produkt 1

HCID 53710128HCID 53710128, VerbindungAusbeute 40 %

Versuchsvorschrift

This compound was prepared according to the method of Preparation 3, using 750 mg (3.67 mmol, 1.0 equiv) 3-ethyl-1H-indazole-6-carboxylic acid methyl ester and 0.38 mL (4.04 mmol, 1.1 equiv) 2-bromopropane as starting materials to give 359 mg (40%) of a clear oil: HRMS calcd for C14H18N2O2+H: 247.1448. Found: 247.14530.

Aufarbeitung

customThis compound was prepared
customaccording to the method of Preparation 3

Quellen und Nachweise

ORD-Eintrag: ord-56cbee09e91d48b99252c0fc270f9f60
Quelldatensatz: uspto-grants-2001_07
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US06262040B1

Notizen zur Reaktion

Wird geladen…