1-(4-Fluorophenyl)cyclopentanecarboxylic acid → 1-(4-fluoro-phenyl)-cyclopentanecarboxylic acid {(3RS,4SR)-4-(3,4-dichloro-phenyl)-1-[1-(1-methyl-cyclopropanecarbonyl)-piperidine-4-carbonyl]-pyrrolidin-3-yl}-methyl-amide

Reaktionsgleichung

[Cl:1][c:2]1[cH:3][c:4]([CH:9]2[CH2:10][N:11]([C:16](=[O:17])[CH:18]3[CH2:19][CH2:20][N:21]([C:24](=[O:25])[C:26]4([CH3:29])[CH2:27][CH2:28]4)[CH2:22][CH2:23]3)[CH2:12][CH:13]2[NH:14][CH3:15])[cH:5][cH:6][c:7]1[Cl:8].[F:30][c:31]1[cH:32][cH:33][c:34]([C:37]2([C:42](=[O:43])[OH:44])[CH2:38][CH2:39][CH2:40][CH2:41]2)[cH:35][cH:36]1>>[Cl:1][c:2]1[cH:3][c:4]([CH:9]2[CH2:10][N:11]([C:16](=[O:17])[CH:18]3[CH2:19][CH2:20][N:21]([C:24](=[O:25])[C:26]4([CH3:29])[CH2:27][CH2:28]4)[CH2:22][CH2:23]3)[CH2:12][CH:13]2[N:14]([CH3:15])[C:42]([C:37]2([c:34]3[cH:33][cH:32][c:31]([F:30])[cH:36][cH:35]3)[CH2:38][CH2:39][CH2:40][CH2:41]2)=[O:44])[cH:5][cH:6][c:7]1[Cl:8]