N-Benzyl-N-methylethanolamine → Biphenyl-2-ylcarbamic acid 1-[2-(benzylmethylamino)ethyl]piperidin-4-yl ester

HRID 13855

Reaktionsgleichung

Reaktionsgleichung von HRID 13855
[CH2:1](N(C)CCO)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH:13]1[CH2:18][CH2:17][CH:16]([O:19][C:20](=[O:34])[NH:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=2[C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[CH2:15][CH2:14]1>>[CH2:1]([CH2:18][NH:13][CH2:14][CH2:15][N:13]1[CH2:14][CH2:15][CH:16]([O:19][C:20](=[O:34])[NH:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=2[C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[CH2:17][CH2:18]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Komponenten

3

Edukt 2

HCID 66876N-Benzyl-N-methylethanolamineHCID 10851461Biphenyl-2-ylcarbamic Acid Piperidin-4-yl Ester

Produkt 1

HCID 57436142Biphenyl-2-ylcarbamic acid 1-[2-(benzylmethylamino)ethyl]piperidin-4-yl ester

Versuchsvorschrift

The title compound was prepared by mesylation of N-benzyl-N-methyl ethanolamine, which was then reacted with biphenyl-2-ylcarbamic acid piperidin-4-yl ester in an alkylation reaction.

Quellen und Nachweise

ORD-Eintrag
ord-2b6299a431304ee5b6b4f157eb29ce52
Quelldatensatz
uspto-grants-2010_06
Patentnummer
US07728144B2

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