HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(4-Aminomethylphenyl)-4-phenyl-5-(4-pyridyl)-imidazole → 2-(4-Biotinamidomethylphenyl)-1-methyl-4-phenyl-5-(4-pyridyl)-imidazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(4-Aminomethylphenyl)-4-phenyl-5-(4-pyridyl)-imidazole | HCID 18771539 | — |
| Edukt | n-Hydroxysuccinimide biotin | HCID 86743017 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 2-(4-Biotinamidomethylphenyl)-1-methyl-4-phenyl-5-(4-pyridyl)-imidazole | HCID 131720117 | — |
Reaktionsschritte
To a solution containing 2-(4-Aminomethylphenyl)-4-phenyl-5-(4-pyridyl)-imidazole (1 equivalent) in DMF was added N-hydroxysuccinimide biotin (1.2 eq). Follwing normal workup and chromatography the title compound was obtained: CIMS (NH3, m/z): 523 (M++H).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06268370B1 |
| Quelldatensatz | uspto-grants-2001_07 |
| ORD ID | ord-ffd7bde2802b4331b941b89e94d5f319 |
| Quellennotiz | uspto-grants-2001_07 |