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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1389903Erstellt: 26. Oktober 2026

Pyridine, 2-(4-methoxyphenoxy)-5-(trifluoromethyl)- → 4-(5-Trifluoromethyl-pyridin-2-yloxy)-phenol

https://huagongshe.com/reaction/1389903

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktPyridine, 2-(4-methoxyphenoxy)-5-(trifluoromethyl)-HCID 155242—
EduktPyridinium chlorideHCID 10176127—
LösungsmittelHydrochloric AcidHCID 313—
LösungsmittelWaterHCID 962—
Produkt4-(5-Trifluoromethyl-pyridin-2-yloxy)-phenolHCID 155241—

Reaktionsschritte

The product from (c) (1.7 g) and excess of pyridine hydrochloride were heated together for 8 hours at 180° C. The mixture was cooled, diluted with water and 2-molar hydrochloric acid, and extracted with ether. The extracts were dried and evaporated to yield an oil identified as the required hydroxy compound.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04246419
Quelldatensatzuspto-grants-1981_01
ORD IDord-397b0ef1c3094488bdaa5eb57e0084bd
Quellennotizuspto-grants-1981_01