HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrogen Bromide → Fenbufen EP Impurity D
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrogen Bromide | HCID 260 | — |
| Edukt | Dihydro-5-(4'-hydroxy-4-biphenylyl)-2(3H)-furanone | HCID 20294315 | — |
| Edukt | 4-(4'-Methoxy-biphenyl-4-yl)-4-oxo-butyric acid | HCID 23005238 | — |
| Produkt | Fenbufen EP Impurity D | HCID 13930818 | — |
Reaktionsschritte
The compound Dihydro-5-(4'-hydroxy-4-biphenylyl)-2(3H)-furanone may be prepared by treating 4'-methoxy-γ-oxo-4-biphenylbutyric acid with hydrogen bromide in acid to produce 4'-hydroxy-γ-oxo-4-biphenylbutyric acid. This in turn is treated with sodium borohydride as described above and then purified with organic solvents to produce the desired product.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04247466 |
| Quelldatensatz | uspto-grants-1981_01 |
| ORD ID | ord-c96a0bb6a0a24592a8b775bb9406c92a |
| Quellennotiz | uspto-grants-1981_01 |