Potassium Carbonate → HCID 70605331, Verbindung

HRID 1390789Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1390789
[C:1]([O:4][C@H:5]1[CH2:10][CH2:9][C@H:8]2[C@H:11]3[C@H:25]([CH2:26][CH2:27][C@:6]12[CH3:7])[C@:19]1([CH2:20][O:21]C(=O)C)[C:14]([CH2:15][C@@H:16]([O:28][CH2:29][CH3:30])[CH2:17][CH2:18]1)=[CH:13][CH2:12]3)(=[O:3])[CH3:2].C(=O)([O-])[O-].[K+].[K+]>CO>[C:1]([O:4][C@H:5]1[CH2:10][CH2:9][C@H:8]2[C@H:11]3[C@H:25]([CH2:26][CH2:27][C@:6]12[CH3:7])[C@:19]1([CH2:20][OH:21])[C:14]([CH2:15][C@@H:16]([O:28][CH2:29][CH3:30])[CH2:17][CH2:18]1)=[CH:13][CH2:12]3)(=[O:3])[CH3:2]

Komponenten

4

Edukt 2

HCID 11430Potassium CarbonateHCID 86736330HCID 86736330, Verbindung

Produkt 1

HCID 70605331HCID 70605331, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

3β-Ethoxy-5-androstene-17β,19-diol diacetate is added to an aqueous methanol solution of potassium carbonate and the reaction solution stirred at room temperature for about 2 hours. The reaction mixture is poured onto water, and the oil which results is extracted into ether. The ether extract is washed with water, dried over magnesium sulfate and concentrated to dryness. Crystallization of the residue from an ether-pentane mixture yields 3β-ethoxy-5-androstene-17β,19-diol 17-acetate.

Aufarbeitung

  1. additionThe reaction mixture is poured onto water
  2. customthe oil which results
  3. extractionis extracted into ether
  4. extractionThe ether extract
  5. washis washed with water
  6. dry with materialdried over magnesium sulfate
  7. concentrationconcentrated to dryness
  8. customCrystallization of the residue from an ether-pentane mixture

Quellen und Nachweise

ORD-Eintrag
ord-f74078a0cc58495790ea1fccafc1a9b3
Quelldatensatz
uspto-grants-1979_02
Patentnummer
US04139617

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