Hydrazine → HCID 45078395, Verbindung

HRID 1391548Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1391548
[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([N+:11]([O-])=O)=[CH:10][C:5]=2[N:4]=[C:3]1[NH2:14].NN>C(O)C>[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([NH2:11])=[CH:10][C:5]=2[N:4]=[C:3]1[NH2:14]

Komponenten

4

Edukt 2

HCID 9321HydrazineHCID 450786361-methyl-5-nitro-1H-benzimidazol-2-amine

Produkt 1

HCID 45078395HCID 45078395, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Reaktionsbedingungen

Temperatur
80 °C

Versuchsvorschrift

To a solution of 1-Methyl-5-nitro-1H-benzoimidazol-2-ylamine (0.19 g, 1 mmol) 10% Pd/C (50 mg) in ethanol (10 ml) was added hydrazine (0.5 ml) and the reaction was heated to 80° C. After TLC showed the starting material to be consumed, the reaction was cooled to rt and passed through a plug of celite. The filtrate was concentrated to give the title compound as an off-white solid. MS (ESI) m/z=163 [M+H]+.

Aufarbeitung

  1. customto be consumed
  2. temperaturethe reaction was cooled to rt
  3. concentrationThe filtrate was concentrated

Quellen und Nachweise

ORD-Eintrag
ord-32cab314128b474a870fd013758380bd
Quelldatensatz
uspto-grants-2008_03
Patentnummer
US07338959B2

Notizen zur Reaktion

Wird geladen…