Tert-butyl 4-hydroxypiperidine-1-carboxylate → HCID 18539076, Verbindung

Reaktionsgleichung

[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH:11](O)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[SH:15][C:16]1[S:17][C:18]2[CH:24]=[CH:23][CH:22]=[CH:21][C:19]=2[N:20]=1>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH:11]([S:15][C:16]2[S:17][C:18]3[CH:24]=[CH:23][CH:22]=[CH:21][C:19]=3[N:20]=2)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Komponenten

Edukt 2

HCID 643502Tert-butyl 4-hydroxypiperidine-1-carboxylate

HCID 178418395HCID 178418395, Verbindung

Produkt 1

HCID 18539076HCID 18539076, Verbindung

Versuchsvorschrift

By a similar manner to Reference Example 35, 1-tert-butoxycarbonyl-4-hydroxypiperidine (1.01 g, 5.0 mmol) was reacted with 2-mercaptobenzothiazole (1.00 g, 6.0 mmol) to give the titled compound as a colorless oily substance (1.54 g, 88%).

Quellen und Nachweise

ORD-Eintrag: ord-73a59c4611f24c3c8a8b031d15f70d16
Quelldatensatz: uspto-grants-2008_03
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07348324B2

Notizen zur Reaktion

Wird geladen…