Propargylamine → HCID 136023135, Verbindung

HRID 1395381Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1395381
[C:1]([NH:3][C:4](=[N:7][CH2:8][CH2:9][S:10][CH2:11][C:12]1[O:13][C:14]([CH2:17][NH:18][CH3:19])=[CH:15][CH:16]=1)SC)#[N:2].[CH2:20]([NH2:23])[C:21]#[CH:22]>CO>[C:1]([NH:3][C:4]([NH:23][CH2:20][C:21]#[CH:22])=[N:7][CH2:8][CH2:9][S:10][CH2:11][C:12]1[O:13][C:14]([CH2:17][NH:18][CH3:19])=[CH:15][CH:16]=1)#[N:2]

Komponenten

4

Edukt 2

HCID 239041PropargylamineHCID 20339222N-cyano-N'-{2-[(5-methylaminomethyl-2-furyl)methylthio]ethyl}-S-methylisothiourea

Produkt 1

HCID 136023135HCID 136023135, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

A mixture of N-cyano-N'-{2-[(5-methylaminomethyl-2-furyl)methylthio]ethyl}-S-methylisothiourea [prepared according to the procedure described in Belgian Pat. No. 857,388] and propargylamine in methanol is stirred and heated under a positive pressure of nitrogen to give, after workup and chromatography, the title compound.

Aufarbeitung

  1. customprepared
  2. temperatureheated under a positive pressure of nitrogen
  3. customto give

Quellen und Nachweise

ORD-Eintrag
ord-7383cece77b44642ad08617167eadc7a
Quelldatensatz
uspto-grants-1980_05
Patentnummer
US04203909

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