HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-(4-Fluorophenoxy)propionic acid → Dimethyl 2-(3-(4-fluorophenoxy)propanamido)malonate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-(4-Fluorophenoxy)propionic acid | HCID 74099 | — |
| Edukt | Dimethyl aminomalonate hydrochloride | HCID 437601 | — |
| Produkt | Dimethyl 2-(3-(4-fluorophenoxy)propanamido)malonate | HCID 50941576 | 80% |
Reaktionsschritte
This compound was synthesized from dimethyl aminomalonate according to the procedure for the preparation of example 2 using 3-(4-fluorophenoxy)propionic acid. The crude residue was purified by flash chromatography on silica (CH2Cl2/MeOH 50:1) to yield the title compound as a white solid (80%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08901132B2 |
| Quelldatensatz | uspto-grants-2014_12 |
| ORD ID | ord-65a150ca252845d0888cf704465dbc65 |
| Quellennotiz | uspto-grants-2014_12 |