2-(2-Phenyl-1,3-thiazol-4-yl)benzoic acid → HCID 67540821, Verbindung
Reaktionsgleichung
[C:1]1([C:7]2[S:8][CH:9]=[C:10]([C:12]3[CH:20]=[CH:19][CH:18]=[CH:17][C:13]=3[C:14]([OH:16])=O)[N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl-].[NH2:22][C:23](=[O:32])[CH:24]([OH:31])[CH:25]([NH3+:30])[CH2:26][CH2:27][CH2:28][CH3:29]>>[NH2:22][C:23](=[O:32])[CH:24]([OH:31])[CH:25]([NH:30][C:14](=[O:16])[C:13]1[CH:17]=[CH:18][CH:19]=[CH:20][C:12]=1[C:10]1[N:11]=[C:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[S:8][CH:9]=1)[CH2:26][CH2:27][CH2:28][CH3:29]Komponenten
3
Versuchsvorschrift
Coupling of 2-(2-phenylthiazol-4-yl)benzoic acid (200 mg, 0.711 mmol) and 1-amino-2-hydroxy-1-oxoheptan-3-aminium chloride (145 mg, 0.737 mmol) in an analogous manner as described for example 1.2 afforded 264 mg of the title compound as white solid.
Quellen und Nachweise
- ORD-Eintrag
- ord-93af8f80e1dd414c8f2bc4559fa1e01d
- Quelldatensatz
- uspto-grants-2014_12