Hydrochloric Acid → 3-{4-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl]-1,4-diazepan-1-yl}propan-1-ol

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Hydrochloric Acid	HCID 313	—
Edukt	3-Chloro-1-propanol	HCID 12313	—
Edukt	1-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl]-1,4-diazepane	HCID 53311543	—
Produkt	3-{4-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl]-1,4-diazepan-1-yl}propan-1-ol	HCID 67324254	—

Reaktionsschritte

The preparation is carried out as already described starting from 95 mg (0.244 mmol) of 1-[4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl]-1,4-diazepane and 30 μl (0.321 mmol) of 3-chloropropan-1-ol. The product is in the form of the hydrochloride.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08907098B2
Quelldatensatz	uspto-grants-2014_12
ORD ID	ord-ff0b552a1687452ea236820f40a5016a
Quellennotiz	uspto-grants-2014_12