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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1404168Erstellt: 27. Oktober 2026

(4-Bromophenyl)boronic acid → 3-(4-{[1-(4-Bromophenyl)-3-(trifluoromethyl)-1H-pyrrol-2-yl]methoxy}-2,3-difluorophenyl)propanoic acid

https://huagongshe.com/reaction/1404168

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt(4-Bromophenyl)boronic acidHCID 79599—
EduktEthyl 3-(2,3-difluoro-4-hydroxyphenyl)propanoateHCID 90404786—
Eduktmethyl 3-(trifluoromethyl)-1H-pyrrole-2-carboxylateHCID 90405535—
Produkt3-(4-{[1-(4-Bromophenyl)-3-(trifluoromethyl)-1H-pyrrol-2-yl]methoxy}-2,3-difluorophenyl)propanoic acidHCID 90406550—

Reaktionsschritte

The title compound was prepared by (a) reacting the product prepared in Step B of Example 1 and 4-bromophenylboronic acid according to the procedure described in Example 1, Step C, (b) then reacting the resulting product according to the procedure in Example 1, Step D, and (c) then reacting the resulting product with ethyl 3-(2,3-difluoro-4-hydroxyphenyl)propanoate according to the procedure described in Example 1, Steps E and F.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08912227B1
Quelldatensatzuspto-grants-2014_12
ORD IDord-ed31395f43244b7194b7843dde2f3c2d
Quellennotizuspto-grants-2014_12