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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1404169Erstellt: 26. Oktober 2026

(4-Bromophenyl)boronic acid → 3-(4-{[1-(4-Bromophenyl)-3-(trifluoromethyl)-1H-pyrrol-2-yl]methoxy}-2,3-difluorophenyl)propan-1-ol

https://huagongshe.com/reaction/1404169

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt(4-Bromophenyl)boronic acidHCID 79599—
EduktEthyl 3-(2,3-difluoro-4-hydroxyphenyl)propanoateHCID 90404786—
Eduktmethyl 3-(trifluoromethyl)-1H-pyrrole-2-carboxylateHCID 90405535—
Produkt3-(4-{[1-(4-Bromophenyl)-3-(trifluoromethyl)-1H-pyrrol-2-yl]methoxy}-2,3-difluorophenyl)propan-1-olHCID 90405861—

Reaktionsschritte

The title compound was prepared by (a) reacting the product prepared in Step B of Example 1 and 4-bromophenylboronic acid according to the procedure described in Example 1, Step C, (b) then reacting the resulting product according to the procedure in Example 1, Step D, (c) then reacting the resulting product with ethyl 3-(2,3-difluoro-4-hydroxyphenyl)propanoate according to the procedure described in Example 1, Step E, and Example 2.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08912227B1
Quelldatensatzuspto-grants-2014_12
ORD IDord-2585871d821e4398a51e08b92a4f4e93
Quellennotizuspto-grants-2014_12