HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(4-Bromophenyl)boronic acid → 3-(4-{[1-(4-Bromophenyl)-3-(trifluoromethyl)-1H-pyrrol-2-yl]methoxy}-2,3-difluorophenyl)propan-1-ol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (4-Bromophenyl)boronic acid | HCID 79599 | — |
| Edukt | Ethyl 3-(2,3-difluoro-4-hydroxyphenyl)propanoate | HCID 90404786 | — |
| Edukt | methyl 3-(trifluoromethyl)-1H-pyrrole-2-carboxylate | HCID 90405535 | — |
| Produkt | 3-(4-{[1-(4-Bromophenyl)-3-(trifluoromethyl)-1H-pyrrol-2-yl]methoxy}-2,3-difluorophenyl)propan-1-ol | HCID 90405861 | — |
Reaktionsschritte
The title compound was prepared by (a) reacting the product prepared in Step B of Example 1 and 4-bromophenylboronic acid according to the procedure described in Example 1, Step C, (b) then reacting the resulting product according to the procedure in Example 1, Step D, (c) then reacting the resulting product with ethyl 3-(2,3-difluoro-4-hydroxyphenyl)propanoate according to the procedure described in Example 1, Step E, and Example 2.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08912227B1 |
| Quelldatensatz | uspto-grants-2014_12 |
| ORD ID | ord-2585871d821e4398a51e08b92a4f4e93 |
| Quellennotiz | uspto-grants-2014_12 |