HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(4-Bromophenyl)boronic acid → 3-(4-{[1-(4-Bromophenyl)-3-(trifluoromethyl)-1H-pyrrol-2-yl]methoxy}-2,3-dimethylphenyl)propanoic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (4-Bromophenyl)boronic acid | HCID 79599 | — |
| Edukt | Ethyl 3-(4-hydroxy-2,3-dimethylphenyl)propanoate | HCID 58566491 | — |
| Edukt | methyl 3-(trifluoromethyl)-1H-pyrrole-2-carboxylate | HCID 90405535 | — |
| Produkt | 3-(4-{[1-(4-Bromophenyl)-3-(trifluoromethyl)-1H-pyrrol-2-yl]methoxy}-2,3-dimethylphenyl)propanoic acid | HCID 90406216 | — |
Reaktionsschritte
The title compound was prepared by (a) reacting the product prepared in Step B of Example 1 and 4-bromophenylboronic acid according to the procedure described in Example 1, Step C, (b) then reacting the resulting product according to the procedure in Example 1, Step D, and (c) then reacting the resulting product with ethyl 3-(2,3-dimethyl-4-hydroxyphenyl)propanoate according to the procedures described in Example 1, Steps E and F.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08912227B1 |
| Quelldatensatz | uspto-grants-2014_12 |
| ORD ID | ord-c5975499a96042d1ba163bb360e60104 |
| Quellennotiz | uspto-grants-2014_12 |