Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Ammonia | HCID 222 | — |
| Edukt | Methyl quinoline-6-carboxylate | HCID 736812 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | Quinoline-6-carboxamide | HCID 11052097 | 88% |
Reaktionsschritte
To a solution of methyl quinoline-6-carboxylate (148 g, 0.79 mol) in methanol (600 ml.), aqueous ammonia (800 ml) was added and then stirred at 45° C. for 12 h. The reaction mixture was concentrated to afford the title compound as a dark red solid (120 g, 88%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US08912331B2 |
|---|
| Quelldatensatz | uspto-grants-2014_12 |
|---|
| ORD ID | ord-3b4f98c9ec754d118faaeff9dba21e23 |
|---|
| Quellennotiz | uspto-grants-2014_12 |
|---|
