(4-Chloro-2-methoxyphenyl)boronic acid → HCID 66576594, Verbindung

HRID 1405195Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1405195
Cl[C:2]1[N:7]=[CH:6][N:5]=[C:4]([NH:8][C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([CH2:15][S:16]([CH3:19])(=[O:18])=[O:17])[CH:10]=2)[N:3]=1.[Cl:20][C:21]1[CH:26]=[CH:25][C:24](B(O)O)=[C:23]([O:30][CH3:31])[CH:22]=1>>[Cl:20][C:21]1[CH:26]=[CH:25][C:24]([C:2]2[N:7]=[CH:6][N:5]=[C:4]([NH:8][C:9]3[CH:14]=[CH:13][CH:12]=[C:11]([CH2:15][S:16]([CH3:19])(=[O:18])=[O:17])[CH:10]=3)[N:3]=2)=[C:23]([O:30][CH3:31])[CH:22]=1

Komponenten

3

Edukt 2

HCID 3858606(4-Chloro-2-methoxyphenyl)boronic acidHCID 219563434-chloro-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amine

Produkt 1

HCID 66576594HCID 66576594, Verbindung

Versuchsvorschrift

Example 32 was prepared under similar conditions as described in the preparation of Example 30 using crude 4-chloro-N-{3-[(methylsulfonyl)methyl]phenyl}-1,3,5-triazin-2-amine and (4-chloro-2-methoxyphenyl)boronic acid (ABCR GmbH & CO. KG). The batch was purified by preparative HPLC.

Aufarbeitung

  1. customExample 32 was prepared under similar conditions
  2. customThe batch was purified by preparative HPLC

Quellen und Nachweise

ORD-Eintrag
ord-a8bd39c2010c4c3d858de02993a03f4b
Quelldatensatz
uspto-grants-2014_12
Patentnummer
US08916557B2

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