HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium borohydride → Benzyl 4-(1-hydroxy-2-methylpropan-2-yl)-3-methoxybenzoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium borohydride | HCID 4311764 | — |
| Edukt | Benzyl 3-methoxy-4-(2-methyl-1-oxopropan-2-yl)benzoate | HCID 86668528 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | Benzyl 4-(1-hydroxy-2-methylpropan-2-yl)-3-methoxybenzoate | HCID 68153567 | — |
Reaktionsschritte
Benzyl 3-methoxy-4-(2-methyl-1-oxopropan-2-yl)benzoate (crude, from step 2) was then treated with MeOH (2 mL) followed by NaBH4 (190 mg, 5.03 mmol). The reaction mixture was stirred for 1 h before it was quenched with brine and extracted with EtOAc. The organic layers were combined, dried over sodium sulfate, and evaporated to give benzyl 4-(1-hydroxy-2-methylpropan-2-yl)-3-methoxybenzoate.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08916565B2 |
| Quelldatensatz | uspto-grants-2014_12 |
| ORD ID | ord-c87e442e248a4000833fe95f7efee9cf |
| Quellennotiz | uspto-grants-2014_12 |