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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1405405Erstellt: 26. Oktober 2026

Sodium borohydride → Benzyl 4-(1-hydroxy-2-methylpropan-2-yl)-3-methoxybenzoate

https://huagongshe.com/reaction/1405405

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktSodium borohydrideHCID 4311764—
EduktBenzyl 3-methoxy-4-(2-methyl-1-oxopropan-2-yl)benzoateHCID 86668528—
LösungsmittelMethanolHCID 887—
ProduktBenzyl 4-(1-hydroxy-2-methylpropan-2-yl)-3-methoxybenzoateHCID 68153567—

Reaktionsschritte

Benzyl 3-methoxy-4-(2-methyl-1-oxopropan-2-yl)benzoate (crude, from step 2) was then treated with MeOH (2 mL) followed by NaBH4 (190 mg, 5.03 mmol). The reaction mixture was stirred for 1 h before it was quenched with brine and extracted with EtOAc. The organic layers were combined, dried over sodium sulfate, and evaporated to give benzyl 4-(1-hydroxy-2-methylpropan-2-yl)-3-methoxybenzoate.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08916565B2
Quelldatensatzuspto-grants-2014_12
ORD IDord-c87e442e248a4000833fe95f7efee9cf
Quellennotizuspto-grants-2014_12