HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Methylanthranilic acid → 2-amino-4-methyl-N-{3-[(R)-2-oxo-3-(3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin-6-yl)-oxazolidin-5-yl]-propyl}-benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Methylanthranilic acid | HCID 75316 | — |
| Edukt | 6-[(R)-5-(3-amino-propyl)-2-oxo-oxazolidin-3-yl]-4H-benzo[1,4]thiazin-3-one | HCID 67303587 | — |
| Produkt | 2-amino-4-methyl-N-{3-[(R)-2-oxo-3-(3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin-6-yl)-oxazolidin-5-yl]-propyl}-benzamide | HCID 86723059 | 82% |
Reaktionsschritte
Starting from 2-amino-4-methylbenzoic acid and 6-[(R)-5-(3-amino-propyl)-2-oxo-oxazolidin-3-yl]-4H-benzo[1,4]thiazin-3-one (described in WO 2010/041219) and using Procedure D, the title compound was obtained as a beige solid (116 mg; 82% yield).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08916573B2 |
| Quelldatensatz | uspto-grants-2014_12 |
| ORD ID | ord-5e996a93ee6e413d96c8f23e31cdaeb4 |
| Quellennotiz | uspto-grants-2014_12 |