Ethyl propiolate → HCID 87180103, Verbindung

Reaktionsgleichung

[C:1]([O:5][CH2:6][CH3:7])(=[O:4])[C:2]#[CH:3].[NH2:8]/[C:9](/[CH3:16])=[CH:10]\[C:11]([O:13][CH2:14][CH3:15])=[O:12]>>[CH2:6]([O:5][C:1](=[O:4])/[CH:2]=[CH:3]/[C:10](=[C:9](/[NH2:8])\[CH3:16])/[C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH3:7]

Komponenten

Edukt 2

HCID 12182Ethyl propiolate

HCID 6437562-Butenoic acid, 3-amino-, ethyl ester, (2Z)-

Produkt 1

HCID 87180103HCID 87180103, Verbindung

Reaktionsbedingungen

Temperatur: 90 °C

Versuchsvorschrift

Ethyl propiolate (39.2 g, 41 mL, 400 mmol) was added to ethyl 3-aminocrotonate (51.75 g, 400 mmol) and the mixture heated at 90° C. for 90 minutes to give a dark red oil. The mixture was allowed to cool, to give the product as a dark orange solid, 87.0 g (96%).

Aufarbeitung

customto give a dark red oil
temperatureto cool

Quellen und Nachweise

ORD-Eintrag: ord-ba5feda558354e9c8dfbbc102b45053b
Quelldatensatz: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08916591B2

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