HCID 67230022, Verbindung → HCID 59529808, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([NH:10][C:11](=[O:13])[CH3:12])[CH3:9])=[CH:4][C:3]=1[N:14]=[C:15]=[S:16].[NH2:17][C:18]1[CH:19]=[C:20]([CH:31]=[CH:32][C:33]=1[NH:34][CH3:35])[C:21]([NH:23][C:24]1[CH:29]=[CH:28][C:27]([Br:30])=[CH:26][CH:25]=1)=[O:22]>CN(C=O)C>[C:11]([NH:10][CH:8]([C:5]1[CH:6]=[CH:7][C:2]([Cl:1])=[C:3]([NH:14][C:15](=[S:16])[NH:17][C:18]2[CH:19]=[C:20]([CH:31]=[CH:32][C:33]=2[NH:34][CH3:35])[C:21]([NH:23][C:24]2[CH:25]=[CH:26][C:27]([Br:30])=[CH:28][CH:29]=2)=[O:22])[CH:4]=1)[CH3:9])(=[O:13])[CH3:12]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
N-[1-(4-Chloro-3-isothiocyanatophenyl)ethyl]acetamide in DMF (2 mL) was added to a mixture of 3-amino-N-(4-bromophenyl)-4-methylaminobenzamide (87 mg, 0.2 mmol, crude material from the step above) in DMF (2 mL) at rt. The mixture was stirred at rt overnight and concentrated. The residue was purified by chromatography to give the sub-title compound. Yield: 130 mg.