HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
trans-3,5-Difluorocinnamic acid → HCID 178501619, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | trans-3,5-Difluorocinnamic acid | HCID 5374941 | — |
| Edukt | Methyl 2-((4-(1H-indol-3-yl)cyclohexyl)amino)-2-(piperidin-4-yl)acetate | HCID 67774409 | — |
| Produkt | HCID 178501619 | HCID 178501619 | — |
Reaktionsschritte
The title compound was prepared from methyl 2-(4-(1H-indol-3-yl)cyclohexyl)amino)-2-(piperidin-4-yl)acetate (from Example 24, step A) and trans-3,5-difluorocinnamic acid, by the method of Example 1, step K, giving a solid that was mostly the more polar cyclohexyl diastereomer by LCMS. Mass spectrum (LCMS, APCI pos.) calcd. for C31H35F2N3O3: 536 (M+H). Found: 536.3.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08921559B2 |
| Quelldatensatz | uspto-grants-2014_12 |
| ORD ID | ord-2ef06bb5c15e40cf9cccf8e4c244993d |
| Quellennotiz | uspto-grants-2014_12 |