2-(2-Fluoro-4-trifluoromethylphenylamino)-3-methylbutanoic acid → 3-(3-Fluorobenzyl)-pyrrolylmethyl 2-(2-fluoro-4-trifluoromethylphenylamino)-3-methylbutanoate
Reaktionsgleichung
[F:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[CH:4][C:3]=1[NH:12][CH:13]([CH:17]([CH3:19])[CH3:18])[C:14]([OH:16])=[O:15].[F:20][C:21]1[CH:22]=[C:23]([CH:32]=[CH:33][CH:34]=1)[CH2:24][C:25]1[CH:29]=[CH:28][NH:27][C:26]=1[CH2:30]O>>[F:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[CH:4][C:3]=1[NH:12][CH:13]([CH:17]([CH3:19])[CH3:18])[C:14]([O:16][CH2:30][C:26]1[NH:27][CH:28]=[CH:29][C:25]=1[CH2:24][C:23]1[CH:32]=[CH:33][CH:34]=[C:21]([F:20])[CH:22]=1)=[O:15]Komponenten
3
Versuchsvorschrift
The acid chloride of 2-(2-fluoro-4-trifluoromethylphenylamino)-3-methylbutanoic acid is reacted with 3-(3-fluorobenzyl)-pyrrolylmethyl alcohol using the procedure of Example 1 to give 3-(3-fluorobenzyl)-pyrrolylmethyl 2-(2-fluoro-4-trifluoromethylphenylamino)-3-methylbutanoate.
Quellen und Nachweise
- ORD-Eintrag
- ord-da00b588098340c19db3706f73ae57a3
- Quelldatensatz
- uspto-grants-1981_02
- Patentnummer
- US04252724
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