Dimethylamine → HCID 21486904, Verbindung
Reaktionsgleichung
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][C:8]([O-:10])=O.[CH3:11][NH:12][CH3:13].[CH2:14]([OH:16])C>>[CH3:14][O:16][CH:7]([C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=1)[C:8]([N:12]([CH3:13])[CH3:11])=[O:10]Komponenten
4
Versuchsvorschrift
A mixture of 18.1 g. of methyl 2-methoxy-2-(2-pyridylacetate and 10 g. of dimethylamine in ethanol is stirred at room temperature for 26 hours. The mixture is concentrated, dissolved in chloroform and extracted with brine. The organic phase is dried over magnesium sulfate and filtered and the solvent is removed under reduced pressure to give 2-methoxy-N,N-dimethyl-2-(2-pyridyl)acetamide.
Aufarbeitung
- additionA mixture of 18.1 g
- concentrationThe mixture is concentrated
- dissolutiondissolved in chloroform
- extractionextracted with brine
- dry with materialThe organic phase is dried over magnesium sulfate
- filtrationfiltered
- customthe solvent is removed under reduced pressure
Quellen und Nachweise
- ORD-Eintrag
- ord-b82a45d711a04f799b71095365eda031
- Quelldatensatz
- uspto-grants-1977_01
- Patentnummer
- US04001241
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