13beta-Ethyl-3-methoxygona-1,3,5(10),8,14-pentaen-17-one → Einecs 227-699-7

HRID 1414971

Reaktionsgleichung

Reaktionsgleichung von HRID 1414971
[CH2:1]([C@:3]12[CH2:11][CH2:10][C:9]3[C:12]4[CH:13]=[CH:14][C:15]([O:20][CH3:21])=[CH:16][C:17]=4[CH2:18][CH2:19][C:8]=3[C:7]1=[CH:6][CH2:5][C:4]2=[O:22])[CH3:2].[H][H]>O1CCOCC1.[Ni]>[CH2:1]([C@:3]12[CH2:11][CH2:10][C:9]3[C:12]4[CH:13]=[CH:14][C:15]([O:20][CH3:21])=[CH:16][C:17]=4[CH2:18][CH2:19][C:8]=3[C@@H:7]1[CH2:6][CH2:5][C:4]2=[O:22])[CH3:2]

Komponenten

5

Edukt 2

HCID 1097930013beta-Ethyl-3-methoxygona-1,3,5(10),8,14-pentaen-17-oneHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 111113Einecs 227-699-7Ausbeute 59,6 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 935NickelKatalysatorHCID 312751,4-DioxaneLösungsmittel

Versuchsvorschrift

Dissolve 13β-ethyl-3-methoxygona-1,3,5(10),8,14-pentaen-17-one (2 g) in dioxan (50 cc) containing Raney nickel (ca. 0.5 g) of moderate activity and shake with hydrogen until 160 cc., the amount corresponding to one molecular proportion has been absorbed. Recrystallize the isolated product from methanol to obtain the title product (1.2 g), m.p. 110°-125°; ultraviolet absorption peak at 280 mμ (ε13,200).

Aufarbeitung

  1. custom, the amount corresponding to one molecular proportion has been absorbed
  2. customRecrystallize the isolated product from methanol

Quellen und Nachweise

ORD-Eintrag
ord-f8615076edb24375a4f9e5b6ba5ce96a
Quelldatensatz
uspto-grants-1977_01
Patentnummer
US04002746

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