N-(2-nitrophenyl)-2-dimethylaminoacetamide → N-(2-aminophenyl)-2-(dimethylamino)acetamide

HRID 1415635Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1415635
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][C:11](=[O:16])[CH2:12][N:13]([CH3:15])[CH3:14])([O-])=O.[H][H]>[Pt]=O.C(O)C>[NH2:1][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][C:11](=[O:16])[CH2:12][N:13]([CH3:14])[CH3:15]

Komponenten

5

Edukt 2

HCID 2958870N-(2-nitrophenyl)-2-dimethylaminoacetamideHCID 178418361HCID 178418361, Verbindung2×

Produkt 1

HCID 16784338N-(2-aminophenyl)-2-(dimethylamino)acetamideAusbeute 77,8 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 82844Platinum oxide (PtO)KatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

N-(2-nitrophenyl)-2-dimethylaminoacetamide (13.8 g), platinum oxide (0.2 g) and ethanol (100 ml) were mixed together and shaken in an atmosphere of hydrogen at atmospheric pressure and laboratory temperature until absorption of hydrogen ceased (4.5 litres of hydrogen were absorbed in 2hours). The mixture was then filtered and the ethanol evaporated off under reduced pressure. The solid residue so obtained was recrystallised from cyclohexane to give N-(2-aminophenyl)-2-dimethylaminoacetamide (9.3 g), m.p. 121°-123° C.

Aufarbeitung

  1. custom(4.5 litres of hydrogen were absorbed in 2hours)
  2. filtrationThe mixture was then filtered
  3. customthe ethanol evaporated off under reduced pressure
  4. customThe solid residue so obtained
  5. customwas recrystallised from cyclohexane

Quellen und Nachweise

ORD-Eintrag
ord-3c74c1875df44f629e9d42366603f025
Quelldatensatz
uspto-grants-1977_01
Patentnummer
US04005217

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