1-(4-Methoxyphenyl)-4-Methyl-2-(4-sulfamoylphenyl)pyrrole → 3-Benzoylpropionitrile

HRID 1415735

Reaktionsgleichung

Reaktionsgleichung von HRID 1415735
Cl[C:2]1[CH:3]=[C:4]([C:10]2[N:11](C3C=C[C:19]([S:22](=O)(=O)N)=CC=3)[CH:12]=[C:13](C)[CH:14]=2)[CH:5]=[CH:6][C:7]=1OC.C[O:27][C:28]1[CH:33]=[CH:32][C:31]([N:34]2[CH:38]=[C:37]([CH3:39])[CH:36]=[C:35]2[C:40]2[CH:45]=[CH:44][C:43]([S:46](=[O:49])(=[O:48])[NH2:47])=[CH:42][CH:41]=2)=[CH:30][CH:29]=1>>[CH2:14]([CH2:13][C:12]#[N:11])[C:10]([C:4]1[CH:5]=[CH:6][CH:7]=[CH:2][CH:3]=1)=[O:27].[CH3:39][C:37]1[CH:36]=[C:35]([C:40]2[CH:45]=[CH:44][C:43]([S:46](=[O:49])(=[O:48])[NH2:47])=[CH:42][CH:41]=2)[N:34]([C:31]2[CH:32]=[CH:33][C:28]([S:22][CH3:19])=[CH:29][CH:30]=2)[CH:38]=1

Komponenten

4

Edukt 2

HCID 218627931-(4-Methoxyphenyl)-4-Methyl-2-(4-sulfamoylphenyl)pyrroleHCID 218628462-(3-Chloro-4-methoxyphenyl)-4-methyl-1-(4-sulfamoylphenyl)pyrrole

Produkt 2

HCID 1384653-BenzoylpropionitrileHCID 99287494-Methyl-1-(4-methylthiophenyl)-2-(4-sulfamoylphenyl)pyrrole

Versuchsvorschrift

In this Step, a phenacyl acetonitrile compound of formula (17) is prepared by alkylating the cyano compound of formula (16) with a phenacyl halide compound of formula (7). This reaction is essentially the same as and may be carried out in the same manner as and using the same reagents and reaction conditions as Step B3 of Method B.

Aufarbeitung

  1. customthe same reagents and reaction conditions as Step B3 of Method B

Quellen und Nachweise

ORD-Eintrag
ord-a257620a77224c62b266e2081366570a
Quelldatensatz
uspto-grants-1999_06
Patentnummer
US05908858

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